Collected Papers

Collected Papers PDF Book Detail Author: Johns Hopkins University. School of Hygiene and Public Health
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Category :
Languages : en
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Journal

Journal PDF Book Detail Author: Chosen Medical Association
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Category :
Languages : en
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Reports

Reports PDF Book Detail Author: Philadelphia General Hospital
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Category :
Languages : en
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Rabbit Biotechnology

Rabbit Biotechnology PDF Book Detail Author: Louis-Marie Houdebine
Publisher: Springer Science & Business Media
ISBN: 9048122279
Category : Medical
Languages : en
Pages : 136

Book Description
Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.

Communications

Communications PDF Book Detail Author: Statens seruminstitut (Denmark)
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ISBN:
Category : Serotherapy
Languages : en
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